Lymphoma aids-related

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Lymphoma, aids-related

b-cell lymphoid tumours that occur in association with aids. Patients often present with an advanced stage of disease and highly malignant subtypes including burkitt lymphoma, immunoblastic large-cell lymphoma, small non-cleaved-cell lymphoma and diffuse large-cell lymphoma. The tumours are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal b-cell lymphoproliferation in aids is a complex result of ebv infection, hiv antigenic stimulation, and T-cell-dependent hiv activation.