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Lim domain

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Lim domain

domain found in proteins required for developmental decisions. Contain 60 residue conserved, cysteine rich, repeats. Named after first 3 genes in group: Lin 11 (c. Elegans required for asymmetric division of blast cells), IsI 1 (mammalian insulin gene binding enhancer protein), mec 3 (c. Elegans required for differentiation of a set of sensory neurons).