Stuck on a problem? Get great tutoring at an affordable price with Chegg. Click here to join and get your 1st 30 minutes Free!

Leukocyte-adhesion deficiency syndrome

From Biology-Online Dictionary
Jump to: navigation, search

Leukocyte-adhesion deficiency syndrome

(Science: syndrome) rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (receptors, leukocyte-adhesion) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterised by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection.