Confused and have questions? We’ve got answers. With Chegg Study, you can get step-by-step solutions to your questions from an expert in the field. If you rather get 1:1 study help, try 30 minutes of free online tutoring with Chegg Tutors.

Kallikrein 9

From Biology-Online Dictionary | Biology-Online Dictionary
Jump to: navigation, search



A member of subgroup serine proteases that confers various physiologic functions in many tissues particularly implicated in cancer cell line.


Kallikrein 9 gene mapped on chromosome 19q13.41 that contains 5 exons in which it is regulated by steroid hormones in breast cancer cell line. It is involved in tumorigenesis and other disease conferring importance in growth and progression implicated in the development of the diseases.

Kallikrein 9 is differentially expressed in ovarian and breast cancer. Human plasma kallikrein is produced in the liver and circulates in the plasma hurdle to molecular weight as a free zymogen once activated by coagulation factor XII displays endopeptidase activity towards peptide bonds afterarginine and lysine and is also able to cleaved inactive precursor proteins to generate active products like prourokinase and plasminogen.

Kallikrein 9 is a possible independent encouraging prognostic marker for early stage optimally exposed ovarian cancer in which concentration in affected patients contains high level in serum.

Gene name: KLK9

Protein name: Kallikrein-9


Kallikrein-like protein 3


See also:


Serine protease