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From Biology-Online Dictionary
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(1) Of or pertaining to something that cannot be dissolved, or solved.

(2) Having the quality of being difficult to solve or explain; insolvable.


Insoluble is often applied to compounds that are poorly soluble or do not readily dissolve in a particular solvent; e.g. oil is insoluble in water.

Word origin: insolubilis : in-, not + solvere, to loosen.

Related forms: insolubility (noun), insolubly (adverb).
Related terms: insoluble soap.

Compare: soluble.
See also: solubility.