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From Biology-Online Dictionary
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1. Of very bad report; having a reputation of the worst kind; held in abhorrence; guilty of something that exposes to infamy; base; notoriously vile; detestable; as, an infamous traitor; an infamous perjurer. False errant knight, infamous, and forsworn. (Spenser)

2. Causing or producing infamy; deserving detestation; scandalous to the last degree; as, an infamous act; infamous vices; infamous corruption.

3. Branded with infamy by conviction of a crime; as, at common law, an infamous person can not be a witness.

4. Having a bad name as being the place where an odious crime was committed, or as being associated with something detestable; hence, unlucky; perilous; dangerous. Infamous woods. Infamous hills, and sandy perilous wilds. (Milton) The piny shade More infamous by cursed Lycaon made. (Dryden)

Synonym: Detestable, odious, scandalous, disgraceful, base, vile, shameful, ignominious.

Origin: Pref. In- not _ famous: cf. L. Infamis. See Infamy.