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Human Genome Project

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Definition

noun

An international scientific research project that began in 1990 and declared completed in 2003, aiming at determining the sequence of chemical base pairs which make up DNA, as well as understanding their function


Supplement

The Human Genome Project is an international research project participated by twenty universities and research centers in the United States, the United Kingdom, Japan, France, Germany, and China.1 It was a large collaborative effort with the intent of determining the sequence of chemical base pairs that make up human DNA, and of identifying and mapping all of the genes of the human genome.2 Genome pertains to the complete set of genetic material in an organism. The genetic material, DNA, is a double stranded molecule consisting of paired nucleotides. The human genome has approximately three billion base pairs in the 23 pairs of chromosomes in the nucleus of a human cell. A human chromosome would have about hundreds to thousands of genes that carry the code for making specific proteins.

The Human Genome Project, which span for 13 years after being declared complete, sequenced the exact order of base pairs using map-based or BAC-based sequencing. The project is regarded as complete although only euchromatic regions were sequenced, not including other regions (i.e. heterochromatic regions). Accordingly, the project is complete as it can be based on the limits of the current technology.1


Abbreviation / Acronym: HGP

See also:

Reference(s):
1 The Human Genome Project Completion: Frequently Asked Questions. (2010). Retrieved from [1].
2 Human Genome Project. Retrieved from [2].