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Homeobox gene

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noun, plural: homeobox genes

One of a group of genes with a common DNA sequence (a homeobox) that code for a homeodomain, and is involved in bodily segmentation and cell differentiation during embryonic development.


Hox gene is an example of a homeobox gene. The homeobox sequence codes for a 60 amino acid protein domain known as the homeodomain. The main role of homeodomain is to act as a switch that controls gene transcription.

See also: Hox gene.