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Histamine release

From Biology-Online Dictionary | Biology-Online Dictionary
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Histamine release

The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of ige, cross-linked by antigen, to the mast cell or basophils fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects.