Gaucher cells

From Biology-Online Dictionary | Biology-Online Dictionary

Gaucher cells

large, finely and uniformly vacuolated cells derived from the reticuloendothelial system, and found especially in the spleen, lymph nodes, liver, and bone marrow of patients with Gaucher's disease; gaucher cells contain kerasin (a cerebroside), which accumulates as a result of a genetically determined absence of the enzyme glucosylceramidase.