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Friend murine leukaemia virus

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Friend murine leukaemia virus

(Science: virology) murine leukaemia virus isolated by Charlotte Friend in 1956 whilst attempting to transmit the Erlich ascites tumour by cell free extracts.

causes an unusual erythroblastosis like leukaemia, in which anaemia is accompanied by large numbers of nucleated red cells in blood. Does not carry a host derived oncogene, but seems to induce tumours by proviral insertion into specific regions of host genome.