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Francisella noatunensis

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A gram-negative nonmotile aerobic and capsulated facultative bacterium involved as a common fish pathogen in warm water particularly tilapia.


Francisella noatunensis is able to survive either inside or outside the host cell which cause fish disease as a results of granulomas that cause problems in fish farms and wild fish. It is isolated in kidney, gill, spleen, liver, heart, gonad, brain and gastrointestinal tract.

Francisella noatunensis is able to live symbiotically with protist and it is found that this bacterium needed cysteine and lack of production of cytochrome oxidase. It has a specific life cycle wherein it enters into phagocytosis to the host cell then phagosomal stage occurs then it discharge to cytosol.

Francisella noatunensis is implicated in francisellosis found in marine and freshwater environments. It is transmitted through a vector that caused pathogenicity. It is also known to cause granulomas in fish that leads to high mortality rates among populations in which contaminated water occurs.

Scientific Classification:

 Kingdom: Bacteria
 Phylum: Proteobacteria
 Class: Gammaproteobacteria
 Order: Thiotrichales
 Family: Francisellaceae
 Genus: Francisella
 Species: Francisella noatunensis

See also:

• Bacteria

• Fish diseases

• Francisellosis