Ets

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Ets

(Science: oncogene) a proto-oncogene that causes leukaemias in chickens.

It is found in E26 transforming retrovirus (v-ets) of chickens and encodes a nuclear protein that can bind dna and regulates the initiation of transcription from a range of cellular and viral promoter and enhancer elements which may help activate and proliferate t lymphocyte cells. There is some interaction between ets and AP1.