Endonuclease

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Definition

noun, plural: endonucleases

A nuclease that cleaves the phosphodiester bond between nucleotides situated within the polynucleotide chain, hence, producing fragments of various sizes.


Supplement

A common example of endonuclease is restriction endonuclease.


Word origin: Greek éndon (within) + nuclease.

Compare: exonuclease

Related terms: