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Eif-2 kinase

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Eif-2 kinase

(Science: enzyme) a dsrna-activated camp-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsrna and atp, eif-2 kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyses the phosphorylation of the alpha subunit of eif-2, leading to the inhibition of protein synthesis.

registry number: EC 2.7.10.-