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Edmans reagent

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The reagent used in Edman method of protein degradation to react with the amine group of the N-terminal amino acid


Edman's reagent or phenylisothiocyanate is one of the many reagents used to label terminal amino acids. It reacts with the free N-terminal amino group of a peptide chain to ultimately form a phenylthiohydantoin for the identification of N-terminal amino acids.


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