Dissociation constant

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(1) A mathematical constant that describes the tendency of a large molecule to dissociate reversibly into smaller components.

(2) The equilibrium constant in a dissociation reaction.


Dissociation constant is a type of equilibrium constant that specifically involves the measure of the propensity of dissociation of a complex molecule into its subcomponents. An example of its application is to describe how tightly a ligand binds to a particular protein.

Also called: equilibrium dissociation constant, ionization constant.

Symbol: Kd

Compare: association constant