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From Biology-Online Dictionary | Biology-Online Dictionary
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1. Discouragement.

2. Want of comfort; uneasiness, mental or physical; disturbance of peace; inquietude; pain; distress; sorrow. An age of spiritual discomfort. Strive against all the discomforts of thy sufferings. (bp. Hall)

Origin: OF. Desconfort, f. Deconfort. See discomfort.