Direct agglutination

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(1) An agglutination (macroscopic clumping) caused by one antibody.

(2) A serological technique in which agglutination of particular reagents is used as an indicator of the presence of an antigen-antibody reaction.


Examples of reagents used in a direct agglutination test are haemagglutination, latex agglutination and coagglutination. The direct agglutination test is usually used as serological test for visceral leishmaniasis.