to give up, the will, courage, or spirit; to be thoroughly disheartened; to lose all courage; to become dispirited or depressed; to take an unhopeful view. I should despair, or at least despond. (Scott's Letters) Others depress their own minds, [and] despond at the first difficulty. We wish that . . . Desponding patriotism may turn its eyes hitherward, and be assured that foundations of our national power still stand strong. (D. Webster)
Synonym: despond, Dispair.