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From Biology-Online Dictionary | Biology-Online Dictionary
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1. To put out of place, order, or rank; to disturb the proper arrangement or order of; to throw into disorder, confusion, or embarrassment; to disorder; to disarrange; as, to derange the plans of a commander, or the affairs of a nation.

2. To disturb in action or function, as a part or organ, or the whole of a machine or organism. A sudden fall deranges some of our internal parts. (Blair)

3. To disturb in the orderly or normal action of the intellect; to render insane.

Synonym: to disorder, disarrange, displace, unsettle, disturb, confuse, discompose, ruffle, disconcert.

Origin: f. Deranger; pref. De- = des- (L. Dis) _ ranger to range. See range, and cf. Disarrange, Disrank.