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From Biology-Online Dictionary
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1. To speak ill of; to depreciate; to malign; to revile. And thou knowest, conscience, i came not to chide Nor deprave thy person with a proud heart. (Piers Plowman)

2. To make bad or worse; to vitiate; to corrupt. Whose pride depraves each other better part. (Spenser)

Synonym: to corrupt, vitiate, contaminate, pollute.

Origin: L. Depravare, depravatum; de- _ pravus crooked, distorted, perverse, wicked.