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Deoxyuridine

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Definition

noun

A deoxyribonucleoside that has uracil attached to a deoxyribose ring.


Supplement

It is an antimetabolite, especially when it is converted to deoxyuridine triphosphate and incorporated to DNA during replication. The presence of side groups bound to the uracil component prevents base pairing, hence, interferes with DNA synthesis.


IUPAC name: 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2, 4-dione
Molecular formula: C9H12N2O5

Synonyms:

  • 2-Deoxyuridine
  • Uracil deoxyriboside
  • Deoxyribose uracil


Compare: uridine.
See also: deoxyribonucleoside.

Related term: Deoxyuridine 1-hydroxylase.