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Dengue shock syndrome

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A dengue hemorrhagic fever of Grade III or Grade IV severity in which there is haemorrhage and circulatory collapse (shock)


Dengue is a viral disease caused by the dengue virus transmitted by a mosquito bite, especially Aedes spp. (e.g. A. aegypti). In 2009, the World Health Organization classified dengue into two groups: uncomplicated and severe. The uncomplicated type is one in which disease does not progress to any complications. The symptoms are relatively milder. The symptoms are generally as follows: acute fever of over 40 °C or 104 °F, headache (especially behind the eyes), an itchy, measle-like rash, and platelet count below the normal level. The severe type of dengue is one that leads or is associated with complications. The dengue haemorrhagic fever is a complication caused by infection of a dengue virus. It is potentially lethal such as in immunocompromised patients or in patients exposed to dengue virus of another strain. It is characterized by further severe symptoms such as haemorrhages in the skin, gastrointestinal tract, and mucosa. There is also plasma leakage resulting in fluid in the abdomen and lungs. The World Health Organization further classified the dengue haemorrhagic fever based on severity. It has four grades: Grade I, II, III, and IV. Grades III and IV are associated with the so-called dengue shock syndrome.

In Grade III and Grade IV, there is a clinical evidence of shock (i.e. a considerable decrease in blood pressure or a circulatory collapse). In Grade IV though the shock is so severe that blood pressure and pulse are hardly detected.

Abbreviation / Acronym:

  • DSS

See also: