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Crigler-najjar disease

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Crigler-najjar disease --> crigler-najjar syndrome

(Science: syndrome) a rare genetic defect (autosomal recessive) where there is the inability to form bilirubin glucuronide due to the absence of the enzyme bilirubin-glucuronoside glucuronosyl transferase, finding include jaundice and irreversible brain damage in the severe form.

Inheritance: autosomal recessive.