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Cleidocranial dysostosis

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Cleidocranial dysostosis

(Science: paediatrics) An inherited disorder of bone development transmitted with an autosomal dominant pattern.

characteristics include absent or incompletely formed collar bones, dental abnormalities, joint laxity and a characteristic facial appearance (heavy brow, protruding jaw, wide nasal bridge and malaligned teeth).

Inheritance: autosomal dominant.