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Chromosomal duplication

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Definition

noun

Duplication of an entire or a portion of a chromosome.


Supplement

Chromosomal duplication may lead to mutation, and to disorders such as Pelizaeus-Merzbacher disease (PMD), a rare central nervous system disorder commonly caused by a complete duplication of the region of the X chromosome containing the PLP1 gene.


Synonyms:


Compare: deletion mutation.
See also: mutation.