Capsular precipitation reaction

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A biochemical reaction in which anticapsular antibodies bind to the capsule of a bacterium, resulting in the swelling of the capsule surrounding a bacterium such that its outlines become more clearly demarcated and therefore become more conspicuous, especially under the microscope.


It is done especially with bacteria that form capsules, such as Streptococcus pneumoniae and Haemophilus influenzae. The capsule becomes more conspicuous under a microscope after the capsular antigen has combined with a specific antibody.