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Campylobacter fetus

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A gram-negative spirally slender curved organism that adheres to intestinal tracts implicated to interrupt the reproductive cycle causing abortions in both human and animals.


Campylobacter fetus is enclosed with an S layer of crystalline surface proteins that consists of 1820 genes containing two membranes and thin cell wall that acts as pathogen inhabited anywhere in the body wherein the S protein revealed to encompass virulence factor in resistance to the immune defense mechanisms. Its S layer protein has a size of at least 97-149kDa fasten to the N terminus of the cell wall lipopolysaccharide and has one DNA inversion.

Campylobacter fetus used flagella for movement by proton motive force for energy and grows at the atmosphere high in carbon dioxide with minimal oxygen and nitrogen. It can survived in an aerobic environment like respiratory type of metabolisms and it does not ferment in which energy generates from amino acids and tricarboxylic acid intermediates.

Campylobacter fetus is mainly found in the intestinal tract which in some cases leads to abortions where it interacts and disrupts reproduction due to its surface layer proteins that has antigenic variations hoaxing the immune system. Animals including reptile, birds and other mammalian vertebrates mostly infected by this bacterium when ingested where it invades the mucus cell whereas human is rarely infected yet can accidentally ingest the bacterium and suffer severe inflammation of intestinal tract.

Scientific classification:

Kingdom: Bacteria
Phylum: Proteobacteria
Class: Epsilon Proteobacteria
Order: Campylobacterales
Family: Campylobacteraceae
Genus: Campylobacter
Species: Campylobacter fetus

See also:


Reproductive cycle