Burkholderia pseudomallei is saprophytic and does not form spores that is able to infect both animals and humans via inhalation, open wounds and ingestion in which incubation period last from days to a couple of years thus, make individual to be infected without realizing it. It is able to grow in neutral pH to slightly acidic environment containing an active Type VI secretion system and expresses toxin known as lethal factor.
Burkholderia pseudomallei can cause melioidosis in humans that normally infects the lungs where pneumonia and bronchitis are common outcome from these bacteria as well as blood disease and heart disease which is particularly dangerous since it can take various different route in an unusual manner once it infects thus, makes these bacteria named as The Great Mimicker.
Burkholderia pseudomallei infections formed lung lesions and ulcerations of mucous membranes in the upper respiratory tract wherein treatment is intensive since this bacterium is resistance to most antibiotics. It has the capability to invade cells and polymerized actin to spread from cell to cell leading to cell fusion and construction of multinucleated giant cells.
Class: Beta Proteobacteria
Species: Burkholderia pseudomallei