Brca1 protein

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Brca1 protein

Phosphoprotein encoded by the BRCA1 gene (genes, BRCA1). It has limited sequence similarity with known proteins. In normal cells the brca1 protein is localised in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localised mainly in the cytoplasm. (science 1995;270(5237):713,789-91)