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Bombay phenomenon

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Bombay phenomenon

a rare recessive trait at a locus that ordinarily manufactures H substance, the precursor from which the a and B phenotypes are elaborated; the mutant causes failure to produce H substance and no matter what the genotype at the ABO locus, the phenotype is O. The bombay phenomenon is epistatic to the ABO locus.

Origin: Bombay, india, where first reported