Bence jones protein

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Bence jones protein

(Science: haematology, oncology) These proteins are dimers of immunoglobulin light chains, normally produced by plasma cells. Bence jones proteins are sufficiently small to be excreted by the kidney.

It is a characteristic protein found in the urine of most patients with multiple myeloma. It can be used to help in diagnosis of the disease and to monitor the response to treatment. Quantification requires a 24 hour urine collection.

See: bence jones reaction