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Anchorage dependence

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A need for contact and anchorage to a stable surface by some cells in order for them to grow, function, and divide, especially even when grown in cell cultures.


Anchorage dependence is necessary for cells to spread or divide (mitosis). The cells that typically need a stable surface for growth would normally be unable to grow in a cell culture. Malignant cells, on the other hand, would still be capable of growing in the absence of anchorage dependence. Hence, this feature is used to determine the nature of the cells by growing them in cell cultures.


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