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Adair-koshland-nemethy-filmer model

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Adair-koshland-nemethy-filmer model --> Koshland-Nemethy-Filmer model

(Science: biochemistry, chemistry) a model to explain the allosteric form of cooperativity; in this model, in the absence of ligands, the protein exists in only one conformation; upon binding, the ligand induces a conformational change that may be transmitted to other subunits.

Synonym: adair-koshland-nemethy-filmer model, induced fit model.