Acute inclusion body encephalitis

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Acute inclusion body encephalitis --> herpes simplex encephalitis

The most common acute encephalitis, caused by HSV-1; affects persons of any age; preferentially involves the inferomedial portions of the temporal lobe and the orbital portions of the frontal lobes; pathologically, severe haemorrhagic necrosis is present along with, in the acute stages, intranuclear eosinophilic inclusion bodies in the neurons and glial cells.

Synonym: acute inclusion body encephalitis, herpes encephalitis.