Acute haemorrhagic leukoencephalitis

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Acute haemorrhagic leukoencephalitis --> acute necrotizing haemorrhagic encephalomyelitis

a fulminating demyelinating disorder of the central nervous system that affects mainly children and young adults. Almost always preceded by a respiratory infection, characterised by the abrupt onset of fever, headache, confusion, and nuchal rigidity, soon followed by focal seizures, hemiplegia, or quadriplegia, brainstem findings, and coma; the csf shows evidence of an inflammatory process; due to the massive destruction of the white matter of one or both hemispheres, often accompanied by similar destruction of the white matter of the brainstem and cerebellar peduncles; of unknown aetiology.

Synonym: acute haemorrhagic leukoencephalitis, acute necrotizing haemorrhagic leukoencephalitis.