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plural: abiogeneses

a·bi·o·gen·esis, [eɪbaɪəʊˈdʒɛnəsɪs]

(1) The theory postulating that primitive life originated from nonliving matter (e.g. simple organic compounds) over a span of millions of years; autogenesis

(2) Spontaneous generation, i.e. the previously popular notion that living organisms could spontaneously arise or develop from nonliving matter



Abiogenesis is one of the modern evolutionary theories on how life originated. It used to refer to the now-discredited hypothesis of spontaneous generation. It was once believed that complex living organisms such as mice, maggots, etc. could arise spontaneously from nonliving matter. This notion used to be popular that it was long held by early thinkers for many years until experiments by Louis Pasteur and others proved it to be false. Now, this theory is superseded by biogenesis, which asserts that living things can only be produced by another living thing, and not by a non-living thing. The modern hypothesis of abiogenesis is now restricted in the presumption that the relatively simpler, earliest forms of life arose from nonliving matter, such as organic compounds, and the process that eventually led to this transition was gradual, not a single event, and estimated to have taken place for over millions of years.

Obsolete abiogenesis

Spontaneous generation refers to the previously popular thought that the apparently complex living things (such as maggots) could form from inanimate objects in a matter of minutes, hours, days, or years. It could also pertain to the process that supposedly led to the formation or development of a living thing from a nonliving thing.

One of the most influential proponents of the theory of spontaneous generation is Aristotle. He believed that plants and animals reproduce by spontaneous generation apart from sexual and parthenogenetic means. According to his book, History of Animals, while some animals could grow from their parent, others could grow spontaneously.[1] Jean Baptiste van Helmont (12 January 1580 – 30 December 1644), a Flemish chemist, physiologist, and physician, came up with a recipe to create mice. According to him, the wheat would transform into mice in after about 21 days by allowing the leaven to react in the shirt with fumes from wheat. As for his recipe for scorpions, the ingredients were a carved brick filled with basil. These were just one of the prevailing thoughts on how life could emerge from inanimate objects.[2]

In spontaneous generation, people thought that a living organism could appear from non-living materials, without the need of a biological precursor, such as a parent. This has become an obsolete thought when it was demonstrated to be a fallacy by verifiable experiments, especially those of Francesco Redi (18 February 1626 – 1 March 1697), the Italian physician and naturalist who was the first to refute spontaneous generation, and Louis Pasteur (December 27, 1822 – September 28, 1895), a French biologist, microbiologist and chemist that irrefutably disproved it. With the advent of laboratory tools and microbial techniques, empirical evidence demonstrated that living things could not be generated spontaneously from inanimate objects. Only living things are capable of reproducing another life. Thus, the theory of spontaneous generation became obsolete and supplanted by the theory of biogenesis. The basic tenet of biogenesis lies on the thought that life arises from similar life forms. The terms abiogenesis and biogenesis were coined by Thomas Henry Huxley (4 May 1825 – 29 June 1895). He proposed that the term abiogenesis be used to refer to the process of spontaneous generation whereas the term biogenesis, to the process where life arises from similar life.

Modern abiogenesis

The modern hypothesis of abiogenesis holds that the primitive life on Earth originated from lifeless matter and it took millions of years to transpire. This theory is the widely-accepted premise on the origin of life. It is different from the obsolete abiogenesis. In its modern context, it speaks of living things that were not yet as complex or elaborate as the life forms of today.

How abiogenesis occurred is still a mystery. It probably incorporated various processes such as self-replication, self-assembly, autocatalysis, and cell membrane formation. Life is built upon the four major biomolecules: carbohydrates, lipids, amino acids, and nucleic acids. Of these biomolecules, the nucleic acid, RNA, can function as both a genetic material and a catalyst. Thus, it is hypothesized that the primitive life was likely RNA-based and that life emerging from the non-living came about as a gradual process that took millions of years. And, this transformation of non-living matter into living entity has not been repeated since then. From the initially simpler forms, living things became more and more complex and they diversified. They have become more adapted and sophisticated as manifested by the evolution of their elaborate physical and genetic attributes.

Other evolutionary thoughts

Earth is presumed to be about 4.54 billion years old and life likely started around 3.5 billion years ago or earlier. According to the theory of primordial soup, the primitive Earth is hypothesized to resemble a soup where organic compounds were synthesized in a large body of water. In Miller-Urey experiment, the simulated-primitive Earth favored the chemical syntheses of the fundamental structures of the cell membrane. One of them was phospholipids, which by nature are capable of forming lipid bilayers.

One of the well-known theory is the RNA world hypothesis. It holds that primordial life was based on RNA, being a genetic material, and at the same time, a catalyst. The RNA-based life might have dominated the primitive Earth and served as the descendants of the current life on Earth. RNA, as well as DNA, components might have come from and synthesized in the asteroids from the outer space. They probably reached the Earth through meteorites. NASA reported that they found RNA and DNA nucleobases (e.g. adenine, guanine) in meteorites.[3] They could have led to the spontaneous creation of RNA and DNA on Earth.


Research on abiogenesis encompasses molecular biology, biochemistry, biophysics, astrobiology, paleontology, and oceanography. Scientists explore to find fossil evidence that will shed light to the origin of life, particularly the origin of the major biomolecules.

As of 2017, the 3.77 to 4.28 billion year-old fossil found in Quebec, Canada, is regarded as the oldest proof of life on Earth. It suggests that life began after the ocean formation, which occurred 4.4 billion years ago. .[4]



  • origin: word (translation, "meaning")
  • Ancient Greek ἀ- (a-, meaning “not”)
  • Ancient Greek βῐ́ος (bíos, meaning “life”)
  • Ancient Greek γένεσις (génesis, “origin”) (


  • autogenesis
  • biopoiesis
  • abiogeny


  • abiogenetic (adjective, of, or pertaining to, abiogenesis)

Further reading




  1. Aristotle. (1910) [c. 343 BCE]. "Book V". History of Animals. Translated by D'Arcy Wentworth Thompson. Oxford: Clarendon Press. ISBN 90-6186-973-0. Retrieved from
  2. Simon, S. (2014, June 4). Fantastically Wrong: Why People Once Thought Mice Grew Out of Wheat and Sweaty Shirts. Retrieved from
  3. NASA - NASA Researchers: DNA Building Blocks Can Be Made in Space. (2011, January 1). Retrieved from
  4. Dodd, M., Papineau, D., Grenne, T., Slack, J., Rittner, M., Pirajno, F., … Little, C. (2017). Evidence for early life in Earth’s oldest hydrothermal vent precipitates - White Rose Research Online. Whiterose.Ac.Uk.

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