macromolecules

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twoods16
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macromolecules

Post by twoods16 » Tue Feb 20, 2007 3:46 am

how can the properties of individual subunits be used to predict the properties of biological macromolecules (protein, carbs, nucleic acis and lipids)

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mith
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Post by mith » Tue Feb 20, 2007 3:57 am

By calculating the interaction of intermolecular forces exhibited by each subunit and it's surroundings and finding the conformation that is most likely.
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MrMistery
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Post by MrMistery » Tue Feb 20, 2007 11:09 am

there are some computer programs that do this for you i think.
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radu
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Post by radu » Tue Feb 20, 2007 11:31 am

and you can even participate at that: search for Rosetta _at_ home (can't give you a link because i must have at least 5 posts)
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Post by Vagabond » Tue Feb 20, 2007 1:23 pm

The properties of individual subunits of a macromolecule can help predict function basically by comparing them to other subunits of other macromolecules with know function. For example, take a protein, a phosphates, which has a subunit which de phosphorylates (removes a phosphate) from a particular protein. Now if you discover another protein that has a subunit that looks similar to that of the de phosphorylation subunit of our know phosphatase enzyme then you will know that your new protein most-likely will have a similar function. Same goes for other macro molecule functions.

Hope that helps and that I typed that clearly if not just ask another question and I will try and be clearer.
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