discuss the significane of DNA replication

Genetics as it applies to evolution, molecular biology, and medical aspects.

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chenwithasterisk
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discuss the significane of DNA replication

Post by chenwithasterisk » Mon Jan 01, 2007 2:17 am

can anyone professinal give a concise explanation app. 300-400 words?
the answer should be
at scholarship level

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victor
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Post by victor » Mon Jan 01, 2007 11:59 am

DNA replication requires:
1. 4 kinds of dNTP
2. Template strand
3. Mg2+ and Zn2+ ions
4. Enzymes, DNA Polymerase I, II, III; DNA ligase; primase, Helicase, Topoisomerase II.
5. Suitable environment...:lol:

For the rest, you can describe each of them and also the mechanisms which are involved.
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LilKim
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Post by LilKim » Tue Jan 02, 2007 2:21 am

Victor's explanation refers to in-vitro DNA replication ie(PCR)...

In-vivo replication is... slightly different

(i'm not sure which explanation you need)

chenwithasterisk
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Post by chenwithasterisk » Tue Jan 02, 2007 4:09 am

hi,there.

thanks in advance.but the q is based on scholarship level. we dont need to discuss all the mechanism in detail(im assuming so).because description is at the lowest level. :roll:

these are some of my thoughts:
1.DNA replication semi-conservative. this ensures the daughter cells can carry out the same functions as parent cells.

2.helicase unwinds the double strand first,then DNA polymerase 3 adds nucleotides to the strand based on base pairing rules-this ensures the accuracy of DNA replication.

3.DNA replication occurs at many points along the double helix. this makes sure DNA replcation occurs at a rate that we want rather than thousands of years.hehe

p.s. sorry for opposing ur answer, acutally,wat u said seems a bit complicated to me(im just learning that).so i wouldnt know how to include it into my sholarship discussion.
cheers :wink:

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mith
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Post by mith » Tue Jan 02, 2007 4:44 am

You do know scholarship isn't a level...
Living one day at a time;
Enjoying one moment at a time;
Accepting hardships as the pathway to peace;
~Niebuhr

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LilKim
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Post by LilKim » Tue Jan 02, 2007 6:01 pm

check here... http://en.wikipedia.org/wiki/DNA_replication

I think this page will contain the basics of everything that you'll need to write for you essay. Please let me know if you need clarification or further explanation of points.

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victor
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Post by victor » Wed Jan 03, 2007 10:07 am

LilKim wrote:Victor's explanation refers to in-vitro DNA replication ie(PCR)...

In-vivo replication is... slightly different

(i'm not sure which explanation you need)


Umm...what do you mean by slightly different? because that's my professor explained to me. Could you enlighten me about the differences between in vivo and in vitro DNA replication?
Q: Why are chemists great for solving problems?
A: They have all the solutions.

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