confusion in calculating...

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Abu Anzar
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confusion in calculating...

Post by Abu Anzar » Fri Dec 08, 2006 6:31 pm

dear friends,

I do know that I can calculate total lenght of DNA thread by multiplying lenght of 1 single uncoiled DNA thread to no. of Cells.

but the confusion is that:

in our body there is 100 trillion cells
out of which 25 trillions cells are RBC that lacks nucleus therefore it also lacks DNA

so the actual figure of cells in which dna is present 75 trillion
further mitochondria also consist of DNA and it is varibly present in cells.

books and reference says that to calculate tot. lenght of thread I have to multiply its lenght with 100 trillion

now tell me where is 25 trillion RBS + mitochondrial DNA ??

urgent

Thanks in Advance


Syed Abu Anzar Salam
BM Student (2nd yr.)
Karachi
Pakistan
SomeWHERE someTHING IncreaDIBLE is GOING to HaPPEN

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MrMistery
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Post by MrMistery » Fri Dec 08, 2006 7:16 pm

i think the book didn'y think as much as you did...
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter

Abu Anzar
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Post by Abu Anzar » Sat Dec 09, 2006 6:50 am

ummm....

let tell 1 thing that will be enough for me, inshaAllah

what is the size of DNA thread in mitochondria, is it equals to other cell or...

as I know how many mitochondria is present in avg.

so in this way I can proceed ma work

Thanks for your reply, Mr Mistery.
SomeWHERE someTHING IncreaDIBLE is GOING to HaPPEN

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MrMistery
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Post by MrMistery » Sat Dec 09, 2006 7:56 pm

DNA in mitochondria is circular, not linear like in the nucleus
in mammals it's a little over 16.000 bases. at an average of 3.4 angstroms per 10 bases... do the math ;)
but it ain't possible to determine, cause one mitochondrion doesn't have one copy of the dna molecule, but multiple copies, and the number isn't constant. and mitochondria constantly fuse and divide. it's complicated
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter

Abu Anzar
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Post by Abu Anzar » Sat Dec 09, 2006 8:19 pm

hmmmz.

well I am mathematic student :P :) as I am biomedical engineering student.

you are right it is complicated and very difficult too. and it is damn difficult to calculate its lenght, thats why I think in book doctors directly took 100 trillion cells instead of going in thought that mitochondria also consist of dna etc.

now what I will do, simply scan different abstracts, net to find out standard no. dna in mitochondria in mammals

plus eat ma biochem teacher's brain :twisted:

shukriya = thanks for all u did, Mr Mistery
SomeWHERE someTHING IncreaDIBLE is GOING to HaPPEN

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