antimicrobials

About microscopic forms of life, including Bacteria, Archea, protozoans, algae and fungi. Topics relating to viruses, viroids and prions also belong here.

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biochan
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antimicrobials

Post by biochan » Sun Oct 29, 2006 9:05 pm

Does anyone could explain (or link) the importance of polarity of an antimicrobial agent in effectiviness of inhibiting bacteria.
thanks a lot in advance

RuNkLi
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Post by RuNkLi » Mon Jun 04, 2007 2:32 pm

antimicrobial peptides for example which are positivly charged can interact with the negativley charged bacterial membrane (forming pores). so this can be the first step of mode of action of the antimicrobial peptide.

selamlar

ilknur

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Post by Ewa » Wed Jul 04, 2007 6:37 pm

I hope this is not against the forum's rules

interesting review on antimicrobial peptides - freely available
http://dx.doi.org/10.2478/s11535-007-0010-5

explains a lot regarding the mechanism of their action - at least to me :)

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