this is the topic....i dont understand!

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phoebe3p
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this is the topic....i dont understand!

Post by phoebe3p » Thu Oct 19, 2006 4:04 am

...this is the archive....pleaz if anyone have time to read it. PLEAZ DO IT...i would like you to explain me some parts i dont get....
...
...
.. and again, if anyone know spanish pleaz LET ME KNOW IT!!!..YOU WOULD HELP ME A LOT,

thanks!

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mith
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Post by mith » Thu Oct 19, 2006 4:45 am

which parts dont you get?
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Leecosta
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Post by Leecosta » Thu Oct 19, 2006 11:48 pm

why do you need to know spanish, i know a bit of the language
:)

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kjle
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Post by kjle » Fri Oct 20, 2006 10:12 am

uhh i take it she's not looking to learn spanish...maybe just her first language, easier to converse in
- disarm you with a smile

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phoebe3p
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no no no

Post by phoebe3p » Sat Oct 21, 2006 12:38 am

I KNOW SPANISH!.., WHAT WOULD BE GREAT IS TO FIND SOMEONE WHO KNOWS SPANISH SO HE OR SHE CAN EXPLAIN ME SOME READINGS I DONT UNDERSTAND BECAUSE THEY ARE IN ENGLISH.....

this is another reading, talks about : Molecular architecture of a kinetochore - microtubule attachment site.

Abstract: Kinetochore attachment to spindle microtubule plus-ends
is necessary for accurate chromosome segregation during
cell division in all eukaryotes. The centromeric DNA of each
chromosome is linked to microtubule plus-ends by eight
structural-protein complexes1−9. Knowing the copy number
of each of these complexes at one kinetochore–microtubule
attachment site is necessary to understand the molecular
architecture of the complex, and to elucidate the mechanisms
underlying kinetochore function. We have counted, with
molecular accuracy, the number of structural protein complexes
in a single kinetochore−microtubule attachment using
quantitative fluorescence microscopy of GFP-tagged kinetochore
proteins in the budding yeast Saccharomyces cerevisiae. We
find that relative to the two Cse4p molecules in the centromeric
histone1, the copy number ranges from one or two for inner
kinetochore proteins such as Mif2p2, to 16 for the DAM–
DASH complex8,9 at the kinetochore–microtubule interface.
These counts allow us to visualize the overall arrangement
of a kinetochore–microtubule attachment. As most of the
budding yeast kinetochore proteins have homologues in higher
eukaryotes, including humans, this molecular arrangement is
likely to be replicated in more complex kinetochores that have
multiple microtubule attachments.




GEE!!..I REALLY NEED HELP...COULD ANYONE EXPLAIN ME THIS IN OTHER WORDS...

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