Cot Curves and kinetic complexity

[nhbio13]

Cot Curves and kinetic complexity

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Post by nhbio13 » Wed Oct 18, 2006 8:55 am

I am having trouble with Cot curves (renaturation) of say mammalian DNA (has unique, moderately repetitive, and highly repetitive sequences) with a clear scale on both axis' to read of %renatured and Cot values. I also have the genome size (in base pairs).

How do I compute the kinetic complexity in base pairs and cot1/2 values of each sequence (moderately, highly, unique)?

Thanks!

Jeffrey