pepsins

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promage
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pepsins

Post by promage » Fri Sep 29, 2006 7:04 am

I have learnt that pepsin digests proteins to polypeptides, and I have also learnt that enzymes which are biological catalysts are made of protein. So, my question is, wouldn't pepsin digest itself since it is made of protein?

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asutoshsahu
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Post by asutoshsahu » Fri Sep 29, 2006 7:25 am

Similarly I can ask u If our stomach get digested by its own digestive juice . answer is of course not.
An enzyme has a certain conformation which targets a specific type of protein and so it can' digest itself which is not the right confromation and it is not also energitically favourable.

promage
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Post by promage » Fri Sep 29, 2006 11:31 pm

Oh, what about our hormones?
My biology teacher told our class that trypsin from the pancreas is able to digest insulin when both of them are put together.

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Poison
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Post by Poison » Sat Sep 30, 2006 10:26 pm

That question was asked previously. (By me :lol: )
And the answer is,proteases DO digest themself. That's why you continuously produce it.

Here is the topic:

viewtopic.php?t=1249
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