Human Anatomy, Physiology, and Medicine. Anything human!

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Post by JennJenn73_angel » Fri Apr 29, 2005 12:09 am

Chloride ions, Cl-, follow actively transported Na+ ions from the nephron into the blood. would you not expect the Cl- concentration to decrease as fluids are extracted along the nephron? What causes the discrepancy?

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Post by star21 » Tue May 10, 2005 10:21 pm

active transport, the carryer proteins dont allow this movement

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Post by MrMistery » Wed May 11, 2005 7:57 pm

Actually, most of the Na+ is not transported through a regular ion channel. It is used to transport glucose back into the blood thorugh a permease(simport transport). Some of the ions ar later absorbed through ion channels. In the permease it is simple: there is no place for the Cl- ion to bind. In the ion channel, if i remember correctly, you have negatively charged aminoacids at the surface that keep those ions out(electrostatic forces do not let them enter)
Good question..
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