DNA replication

Genetics as it applies to evolution, molecular biology, and medical aspects.

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pdavis68
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DNA replication

Post by pdavis68 » Tue Aug 22, 2006 7:19 pm

I have a question regarding DNA replication...

As I understnad it, you have a coding strand and a template strand. The template strand (or is it the coding strand?) is copied to make mRNA (so the mRNA should look like the coding strand with the Us instead of Ts).

Now, my question is, how exactly does this work? Isn't it possible, out of sheer random probability that a promoter will appear on the wrong strand? In fact, wouldn't there be a lot of them? I realize that it might not be expressed because of histones and supercoiling, but if there are a lot of them, wouldn't some of them, simply by random chance, be expressed?

Maybe I'm confused.

Pete

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fluktuacia
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Post by fluktuacia » Tue Aug 22, 2006 8:12 pm

hmm.. at first is your question about DNA transcription or DNA replication ('cos i think in DNA replication mRNA is not involved, the DNA polymerase binds to RNA primase etc.).. it's a complicated stuff.. maybe this links will help you
http://en.wikipedia.org/wiki/DNA_replication
http://en.wikipedia.org/wiki/Transcription_(genetics)

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