growth of non-transformed cultures

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Arthur
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growth of non-transformed cultures

Post by Arthur » Sat Aug 19, 2006 11:25 pm

Hello

I have a question again about cell cultures. Do non-transformed cultures at general grow as fast as transformed cultures?

Or is it true that the difference between their division rate can be very high, independent if non-transformed cultures have contact or not?

Any help would be great.
Last edited by Arthur on Sun Aug 20, 2006 6:37 pm, edited 1 time in total.

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MrMistery
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Post by MrMistery » Sun Aug 20, 2006 9:36 am

malignant cells take just as long as normal cells to divide, but they do not go through any S phase(or a very short phase). normal cells need growth factors in order to divide, but even so i don't know if they do it as fast as the cancer cells.
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Arthur
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Post by Arthur » Sun Aug 20, 2006 6:35 pm

Thank you, this answer is helping me. Wish you an enjoyful end of weekend :)

weesper
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Post by weesper » Wed Aug 23, 2006 7:16 am

Actually non-transformed cells such as fibroblasts grow faster than transformed cells. If you're growing a cell line from patient material this is your main concern that it might get overrun with normal cells. Cancer cells form tumors because these cells do not go into apoptosis pushing the total balance towards growth albeit slower.

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