Cell cycle checkpoints

Genetics as it applies to evolution, molecular biology, and medical aspects.

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Charlie
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Cell cycle checkpoints

Post by Charlie » Thu Aug 17, 2006 9:22 am

Could someone please tell me in detail what happens in the G1/S checkpoint? I hav been looking everywhere with no result. Thanks

sdekivit
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Post by sdekivit » Thu Aug 17, 2006 9:35 am

have you already searched in 'Molecular Biology of the Cell' bij Alberts et al. Chapter 17 tells you all about the cell cycle and programmed cell death.

Hint: you should something about S-cdk and the ORC. Involved molecules are: Cdc6 and Mcm and the proteincomplex they set up: the pre-replicative complex or pre-RC.

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