I really need help on this problem.

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zeroh6x
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I really need help on this problem.

Post by zeroh6x » Sun Aug 06, 2006 2:17 pm

If we were to label the CO2's on citrate, we would find that they are not dealt with equivalently by enzymes in the TCA cycle. Using appropriate vocabulary, explain how the CO2's differ. Describe how their difference can be observed in the TCA reactions.

p.s. I only know how TCA is working. Pyruvate is oxidized into Co2 and H2O in the TCA reactions. But i don't seem to understand why they are not dealt with equivalent by enzymes and how they differ then what differecne can be observe? i tried to solve this problem but couln'dt make it. It will be great if anyone can help me out.

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Post by sdekivit » Sun Aug 06, 2006 8:18 pm

follow the carbonatoms druing the Krebs cycle and investigate where they end up.

(you'll find that pyruvate will yield ATP during the second cycle in the Krebs cycle)

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Post by zeroh6x » Sun Aug 06, 2006 11:24 pm

But that doesn't seemed to answer my question. I am really stuck now

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mith
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Post by mith » Sun Aug 06, 2006 11:50 pm

http://web.indstate.edu/thcme/mwking/tca-cycle.html

I think it might be referring to the isocitrate and ketoglutarate reactions...
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MrMistery
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Post by MrMistery » Mon Aug 07, 2006 5:27 pm

Everything you need is in this diagram. You're welcome.
http://www.ncbi.nlm.nih.gov/entrez/quer ... c4.box.307

And please rename your topic. I moved it to the cell bio forum.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter

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Post by sdekivit » Mon Aug 07, 2006 5:49 pm

MrMistery wrote:Everything you need is in this diagram. You're welcome.
http://www.ncbi.nlm.nih.gov/entrez/quer ... c4.box.307

And please rename your topic. I moved it to the cell bio forum.


Great resource. i love this work :D. This is what i meant with: follow the C-atoms during TCA cycle.

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MrMistery
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Post by MrMistery » Mon Aug 07, 2006 6:02 pm

Alberts beats the heck out of any other cell bio book.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter

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Post by sdekivit » Tue Aug 08, 2006 9:48 am

MrMistery wrote:Alberts beats the heck out of any other cell bio book.


it really does :D

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